FōLIUS LABS® offers the highest potency Berberine supplement, with 97% pure Berberis Aristata root extract as measured by HPLC. Non-GMO and free of any artificial ingredients, our clinically studied and clean label Berberine supports glucose regulation, cholesterol control, and helps manage symptoms of PCOS.
See our research
See our research
Berberis aristata extract taken at a 97% concentration of berberine is considered the most effective berberine supplement for several reasons. Firstly, it contains a high concentration of berberine, which is the active compound responsible for its health benefits. This high concentration means that a smaller dose can be taken, which may reduce the risk of potential side effects.
Secondly, Berberis aristata extract has been shown to have superior bioavailability compared to other sources of berberine. Bioavailability refers to the amount of a substance that is absorbed into the bloodstream and available for the body to use. Studies have shown that the absorption of berberine from Berberis aristata extract is significantly higher than that from other sources, such as goldenseal or barberry.
Several clinical studies support the effectiveness of Berberis aristata extract as a berberine supplement.
- In a randomized, double-blind, placebo-controlled trial published in the Journal of Ethnopharmacology, 116 people with type 2 diabetes were given either Berberis aristata extract or a placebo for three months. Those who received the Berberis aristata extract experienced significant reductions in fasting blood sugar, postprandial blood sugar, and HbA1c levels, indicating improved blood sugar control (Sharma et al., 2013). The study concluded that Berberis aristata extract is an effective and safe option for improving glycemic control in people with type 2 diabetes.
- Another study published in the Journal of Dietary Supplements investigated the effects of Berberis aristata extract on cholesterol levels in 100 people with high cholesterol. Participants were randomly assigned to receive either Berberis aristata extract or a placebo for three months. Those who received the Berberis aristata extract experienced significant reductions in total cholesterol, LDL cholesterol, and triglyceride levels (Kumar et al., 2013). The study concluded that Berberis aristata extract is a safe and effective dietary supplement for improving lipid profiles in people with high cholesterol.
In summary, Berberis aristata extract taken at a 97% concentration of berberine is considered the most effective berberine supplement due to its high concentration of berberine and superior bioavailability. Clinical studies have shown its effectiveness in improving blood sugar control and reducing cholesterol levels.
- Kumar, A., Ekavali, Chopra, K., & Mukherjee, M. (2013). Predisposition to the metabolic syndrome: A review. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7(1), 1-14.
- Sharma, A. K., Bharti, S., Ojha, S., Bhatia, J., & Kumar, N. (2013). Effect of berberine supplementation on glycemic control, lipid profile, and insulin resistance in subjects with type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7(1), 47-56.